Prunus
armeniaca. 杏XìngApricot
Family: Rosaceae
Like almonds, Apricot kernel can be either sweet or bitter. This bitterness is
the definition of the term bitter when describing herbs in Chinese medicine. The
bitterness also corresponds to the toxic amydalin content. Sweet apricot kernel
has very low toxicity, while the toxicity of Bitter apricot, Bitter almond and
Peach kernel is higher.
Crossbreds/highbrids of apricots being sold for producing the fruit usually have
bitter kernels. The Sweet apricot kernel is obtained from traditional trees. 杏果Xìng guǒ Fruit FLAVOR: Sweet and sour
FUNCTIONS
1. Lubricates the Lungs and produces fluids.[6] INDICATIONS
1. Thirst and asthma.[6] CONTRAINDICATIONS: Fresh apricots are not recommended for frequent
or excessive consumption or for people with diarrhea. PREPARATIONS:Commonly eaten fruit
- Quench a thirst- Eat 2 to 3 fresh or dry apricots in the morning and evening
to relieve a dry throat and to quench thirst.[6] 杏仁 Xìng rén
Sweet apricot kernel,
Chinese almond First mentioned in Shennong Ben Cao Jing
text about 220 CE FLAVOR: Pungent and sweet CHANNEL:
Lung, Large Intestine. TOXICITY: Slightly toxic.[5] FUNCTIONS- GROUP:
Antitussive and Expectorant- Clear Breathing
1. Stops coughing and relieves wheezing-[1,6,7]This effect is immediate and has no equal for treating children coughing at
night. A useful preparation with Apricot kernel with a phlegm resolving herb is
She dan chuan bei ye oral liquid.Relieve dyspnea and
asthma.[1]
2. Moistens the intestine and unblocks the bowels.[1,6,7]
3. Expel sputum. Lubricate the Lung. Resolves Phlegm.[1]
4. Lowers rising Lung Qi. Energy tonic.[6]
Lowers excessive Energy.[1] ACTIONS
Antitussive. Hypotensive. Amygalin,
one of the components of Xing ren has been shown to be antitussive in animals.
INDICATIONS
1. Cough and dyspnea due to a range of causes including; failure of Lung Energy
to descend, Heat or Cold, Wind Cold, Dry Heat, Colds with coughing.[1,7]
Because the herb is moist in nature, is is escpecially useful for externally contracted
Dry cough.[1,7] Unproductive coughing.[1]
Asthma.[1]
2. Dryness syndrome of the intestine with constipation. This use of the herb
derives from its high oil content.[7] CONTRAINDICATIONS: Cough due to Yin deficiency, diarrhea. Use with caution
in treating infants and in cases of diarrhea.[7]
Some traditional texts say this herb antagonizes Astragalus propinquus- Huang
Qi, Scutellaria baicalensis- Huang
qin and Pueraria pseudohirsuta-
Ge gen.[7] PATENT COMBINATIONS
- Asthma due to Phlegm Heat: Diffuses
and redirects the Lung Qi downward, alleviates wheezing, transforms Phlegm,
clears Heat
Gingko Nut & Apricot seed- Ding chuang wan. - Cold and Flu with Wind Heat syndrome:Release
Exterior Wind and Clears HeatCold
& Flu Combination- Gan mao qing re chong ji. - Stagnation of Phlegm Heat in the Lungs and throat:Eliminates
Phlegm, Regulates Qi, disperses Stagnation, Drains Dampness, Clears Heat, and
relieves cough Platycodon
Combination- Jie geng wan. - Dryness in the Stomach and Intestines due to heat, causing constipation:Moistens the Intestines, drains
heat, moves the Qi and unblocks the bowelsApricot
seed & Linum- Ma zi ren wan. - Phlegm and Heat in Lung with damage to Lung Yin: Clear
Lung Phlegm Heat, Nourishes Lung Yin, alleviates coughingPlatycodon
& Fritillaria- Qing fei tang. - For stagnation of heat and Phlegm in the Lung:Clears
Heat, eliminates Phlegm, Descends Rebellious Qi, alleviates coughingZhi
shi & Arisaema- Qing qi hua tan wan. - Lung attacked by Warm
Dryness:Releases external dryness,
moistens the Lung and nourishes the Lung Yin. Tonifies Qi and alleviates coughingEriobotrya
& Ophiopogon- Qing zao jiu fei tang. - Constipation due to Blood and Yin deficiency with stagnation of Qi:
Moistens the Intestines, regulates the Qi, nourishes the Yin and
the Blood, unblocks the bowels Linum
& Rhubarb- Run chang wan. - Wind Heat type common cold or flu with cough
at early stage:Releases exterior Wind-Heat, diffuses
the Lung Qi and alleviates cough Morus
& Chrysanthemum- Sang ju wan. - Constipation due to dryness
of the Intestines:Moistens the
Intestines and unblocks the bowelsFive
seeds Combination- Wu ren wan. - Exterior Wind Cold with retention of Phlegm
and Fluids: Releases exterior Wind-Cold, warms the Lung and
Spleen to transform Phlegm and congested fluids, directs rebellious Qi downwards
to relieve cough and dyspnea Minor
blue Dragon Combination- Xiao qing long wan. - Damp Heat painful obstruction: Clears Heat, eliminates
Dampness, unblocks the Channels and Collaterals, relieves painful obstructionStephania
& Blue Atractylodes- Xuan bi tang. - Cold and cough caused by Wind Cold, and dyspnea, it is often used with
Perilla leaf as in Apricot kernel and Perilla powder- Xing su san. Colds and coughing,
unproductive coughing.
- Cough caused by Dry heat, it is used with Mulberry leaf and Fritillary
bulb, as in Decoction of Mulberry leaf and Apricot kernel- Sang xing tang.
- Lung Heat manifesting as cough. It is usually used with Ephedra, Gypsum
and Liquorice, known as Decoction of Ephedra, Apricot kernel, Gypsum and Liquorice-
Ma xing shi gan tang. Asthma, and sore throat.
1. Dry cough due to externally contracted
Wind Cold, with Perilla frutescens- Zi
su ye.[7]
2. Cough caused by Lung Dryness and Heat, with Ophipogon
japonicus- Mai men dong.[7]
3. Non productive Dry cough due to Externally contacted Wind Heat, with Morus
alba- Sang ye.[7]
4. Cough and wheezing due to excess. With Ephedra
sinica- Ma huang. With significant Heat add Calcium
sulphate- Shi gao.[7]
4. Constipation due to deficient Qi and dry Intestines. Use with Cannabis
sativa- Huo ma ren and Angelica polymorpha-
Dang gui.[7]
PREPARATIONS:Decoction-
Kernel 3-10 g crushed or chopped before decocting.[1,3,5,7]
It is added near the end of the decoction.[7]
Good quality if full, intact, non-oily, and bitter. Some sources indicate that
it is better to remove the tip before using.[7]
Because this drug has a slight toxicity, never take large quantities of it. It
should be used very cautiously for infants.[5]
Collected in summer and dried in sunlight. It is used unprepared, or rid of the
precarp and pointed tip after scalding.
- Cure chronic cough- Chew 5 to 10 Sweet apricot seeds once a day to cure chronic
cough and shivering with cold.[6]
- Constipation in the elderly and in pregnant women- Combine 15 g Sweet apricot
seeds, 30 g each of rice and sugar; add wate and crush them to make a cream. Eat
it in the morning and evening.[6]苦杏仁
Kǔ xìng rén Bitter
apricot kernel FLAVOR:
Pungent and bitter TOXICITY: TOXIC
FUNCTIONS 1. Supress cough, relieve asthma.[6]
2. Lubricate intestines.[6] PREPARATIONS:
Bitter apricot seeds are toxic and should not be consumed in fresh or raw forms.[6]
- Dry cough- Prepare 2 pears and remove the seeds. Crush 6 g Bitter apricot seeds
and grind into powder; stuff the powder into the pears and steam for half an hour.
Eat once a day.[6]
- Cough with watery mucus- Boil 9 g Bitter apricot seeds in water with 6 g fresh
ginger and 2 red dates. Drink as tea twice a day.[6]References
[1] Barefoot Doctor's Manual- 1977 Prepared
by the Revolutionary Health Committee of Hunan Province. Original Chinese manual-
Victor W. Sidel. Originally published by Dr Joseph Quin and the Fogarty International
centre, Bethdesda (1974). Madrona Publishers Seattle Washington ISBN 0-914842-52-8
[2] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture
and Herbalism 1981- Henry Lu Chinese Foundations of Natural Health- The Academy
of Oriental Heritage, Vancouver, Canada.
[3] Medicated Diet of Traditional Chinese Medicine - Chief Editor- Hou Jinglun.
Associate Editors- Zhao Xin, Li Weidong, Liu Jianxin, Geng Chun-e, Li Guohua,
Li Shaohua. Geijing. Science & Technology Press 1994. ISBN 7-5304-1735-5/R.
309.
[4] Mediherb- A herbal extract company based in Warwick Qld. 4370 Australia
www.mediherb.com
[5] The Chinese Materia Medica A practical English- Chinese Library of Traditional
Chinese Medicine Publishing House of Shanghai University of Traditional Chinese
Medicine. Director Hu Ximing ISBN 7-81010-111-X/R-110
[6] Chinese System of Food Cures Prevention and Remedies. 1986Lu,
Henry. Sterling Publishing Co., Inc. New York. USA. Distributed in Australia
by Capricorn Book Co. Pty Ltd. Lane Cove, NSW. ISBN 0-8069-6308-5.
[7] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7 Images
1. en.wikipedia.org
by Fir0002 GFDL 1.2
2. commons.wikimedia.org
by Elena Chochkova CC- SA 3.0
3. fourflowerswellness.com
4. growingfruit.org
Inner Path can not take any responsibility for any adverse effects from the
use of plants. Always seek advice from a professional before using a plant medicinally. Constituents
Apricot kernels contains 50% of fatty oils
(including oleic, linoleic. palmitic, stearic and linolenic acids).[1]
Amygdalin, amygdalase and prunase.[1,7]
Hydrolysing amygdalin generates benzaldehyde and hydrocyanic acid, which is
toxic.[1] References
[1] newdrugapprovals.org
[2] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7
Apricot kernels toxin is amygdalin. Bitter
kernels contain higher quantities of amygdalin and amygdalase than sweet kernels.
The variety of tree determines which type of kernel is produced. Hybrids bred
for certain types of apricots tend to have bitter kernels.
On average, bitter apricot kernels contain about 5% amygdalin and sweet kernels
about 0.9% amygdalin. These values produce 0.3% and 0.05% of cyanide. Since
a typical apricot kernel weighs 600 mg, bitter and sweet varieties contain,
respectively, 1.8 and 0.3 mg of cyanide. A fatal dose for humans can be as low
as 1.5 mg/kg body weight.[2]
The L50
of bitter apricot kernels for an adult is around 50-60 kernel,
while for an infant it is around 10 kernels.[1]
Cyanide ion (CN- ) binds to hemoglobin, the oxygen-carrying molecule
in red blood cells. It distributes throughout the body via the bloodstream where
it binds to the metabolic enzyme cytochrome c-oxidase. This prevents cells from
using oxygen and producing energy.[3]
Cooking, removal of the outer coating and mixing with sugar reduces its toxicity.
In cases of overdosage, administration of activitate charcoal and syrup of ipcac
is recommended. The bark of the apricot tree or the cotex of the root has also
traditionally been used as an antidote.[1]
Overdosage of this herb causes dizziness, nausea, vomiting, and headache, which
can progress to dyspnea, spasms, dilated pupils, arrhythmias and coma.[1] References
[1] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7
[2] Cyanide
[Technical document – Chemical/Physical Parameters]. Health Canada. 6 October
2008. Archived from the original on 4 February 2009.
[3] newdrugapprovals.org
Research
Xing ren and Tao
ren are restricted in Australia by TGA despite being used for thousands of
years in Chinese herbs. When are Fu Zi And Ma Huang going to become available in Austalia? Feb
22, 2013
Two of the herbs proposed by the former Chinese Medicine Registration Board of
Victoria to be added to Schedule 1 of the Standard for the Uniform Scheduling
of Medicines and Poisons (SUSMP) remain unavailable to registered Chinese herbal
medicine practitioners with additional endorsement for prescribing these herbs
individually.
The SUSMP, referred to as “The Poisons Standard”, has a Schedule 1 which is empty.
Under the Victorian Poisons List (Schedules 2-9 are adopted automatically by reference
from the national Standard for Uniform Scheduling of Medicines and Poisons), it
is currently illegal for a Chinese herbal medicine practitioner or herbal dispenser
to ‘obtain, possess, use, sell or supply’ certain Chinese herbs listed in the
various schedules of the list. Similar restrictions apply in other states and
territories.
The former Chinese Medicine Registration Board Victoria (ended on 30 June 2012)
prepared a submission for the Victorian Minister for Health recommending the inclusion
of Fu zi and Ma huang (as well as Ban Bian Lian) in Schedule 1 of the Victorian
Poisons List so that Board-endorsed practitioners could safely dispense/prescribe
for patients who would benefit from the use of these herbs based on their professional
justification and an evidence-based approach. Until now, the herbs have failed
to receive the Ministerial approval in Victoria which may have been a basis for
other States to consider similar arrangements.
With national registration now commenced from July 2012, this is now a national
issue and a new strategy is needed to achieve access to those herbs for Chinese
herbal medicine practitioners in Australia.
safflower.com.au
Anti-inflammatory effect of Prunus armeniaca L. (Apricot) extracts ameliorates
TNBS-induced ulcerative colitis in rats.
Minaiyan M, Ghannadi A, Asadi M, Etemad M, Mahzouni P. Abstract
Prunus armeniaca L. (Apricot) is a tree cultivated in different parts of the world.
Apricot kernel as a good dietary supplement has shown antioxidant, anti-inflammatory
and other pharmacologic properties which suggest that it may be functional as
an anticolitis agent. In this study we evaluated the effects of apricot kernel
extract and oil on ulcerative colitis in rats. Rats were fasted for 36 h before
the experiment. Colitis was induced by intra-rectal instillation of 50 mg/kg trinitrobenzene
sulfonic acid in male Wistar rats. Treatments were started 6 h after colitis induction
and continued every 24 h for 5 days. Apricot kernel extract (100, 200, 400 mg/kg
p.o. and 100, 400 mg/kg i.p.) and apricot kernel extract/oil (100, 200, 400 mg/kg
p.o.) were used as experimental treatments and prednisolone (4 mg/kg p.o. or i.p.)
was used as reference drug. On the day 6, colon tissue was removed and macroscopic
and pathologic parameters were evaluated. Ulcer index and total colitis index
as representative of macroscopic and histologic parameters respectively showed
ameliorating effects in experimental groups especially those treated by intraperitoneal
administration route. Results also demonstrated that oil fraction was not able
to potentiate the effects of extract. These data suggest that apricot kernel extracts
(with or without oil) can be introduced for further mechanistic and clinical studies
as a complementary medicine for inflammatory bowel disorders.
PMID: 25657793 PMCID: PMC4314870 Res Pharm Sci. 2014 Jul-Aug;9(4):225-31.
ncbi.nlm.nih.gov
Antioxidant and antimicrobial activities of bitter and sweet apricot (Prunus
armeniaca L.) kernels.
Yiğit D, Yiğit N, Mavi A. Abstract
The present study describes the in vitro antimicrobial and antioxidant activity
of methanol and water extracts of sweet and bitter apricot (Prunus armeniaca L.)
kernels. The antioxidant properties of apricot kernels were evaluated by determining
radical scavenging power, lipid peroxidation inhibition activity and total phenol
content measured with a DPPH test, the thiocyanate method and the Folin method,
respectively. In contrast to extracts of the bitter kernels, both the water and
methanol extracts of sweet kernels have antioxidant potential. The highest percent
inhibition of lipid peroxidation (69%) and total phenolic content (7.9 +/- 0.2
microg/mL) were detected in the methanol extract of sweet kernels (Hasanbey) and
in the water extract of the same cultivar, respectively. The antimicrobial activities
of the above extracts were also tested against human pathogenic microorganisms
using a disc-diffusion method, and the minimal inhibitory concentration (MIC)
values of each active extract were determined. The most effective antibacterial
activity was observed in the methanol and water extracts of bitter kernels and
in the methanol extract of sweet kernels against the Gram-positive bacteria Staphylococcus
aureus. Additionally, the methanol extracts of the bitter kernels were very potent
against the Gram-negative bacteria Escherichia coli (0.312 mg/mL MIC value). Significant
anti-candida activity was also observed with the methanol extract of bitter apricot
kernels against Candida albicans, consisting of a 14 mm in diameter of inhibition
zone and a 0.625 mg/mL MIC value.
PMID: 19330262 Braz J Med Biol Res. 2009 Apr;42(4):346-52. ncbi.nlm.nih.gov