[1] British Herbal Pharmacopoeia 1983 Published by the British Herbal Medicine
Association ISBN 0 903032 07 4.
[2] Herbal Materia Medica Course Notes For Diploma of Naturopathy and Diploma
of Herbalism Students by Lydia Mottram.
[3]
Potter's New Cyclopaedia of Botanical Drugs and Preparations
R.C. Wren Revised by Elizabeth M. Williamson and Fred J Evans. First published
in Great Britain in 1988 and reprinted in 1989 and 1994 by the C. W. Daniel
Company Limited. 1 Church Path, Saffron Walden Essex. Published 1988 Printed
and bound by Biddles, Guildford ISBN 085207 1973.
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[1] British Herbal Pharmacopoeia 1983 Published
by the British Herbal Medicine Association ISBN 0 903032 07 4.
[2] Herbal Materia Medica Course Notes For Diploma of Naturopathy and Diploma
of Herbalism Students by Lydia Mottram.
References
Effects of the Oil and Mucilage from Flaxseed (Linum Usitatissimum)
on Gastric Lesions Induced by Ethanol in Rats
Dugani A, Auzzi A, Naas F and Megwez S
Abstract:
The anti-ulcer activity of the oil and mucilage obtained from flaxseed
(Linum usitatissimum) was evaluated in a rat model of ethanol-induced gastric
ulcer. Our results show that pretreatment of rats with flaxseed oil and flaxseed
mucilage significantly reduced the number and length of gastric ulcers induced
by ethanol. Flaxseed oil was more effective than flaxseed mucilage in reducing
the number of ulcers. The reduction in ulcer severity (cumulative length in
mm) provided by an oral dose of flaxseed oil (5 ml/kg) was more prominent than
that obtained by ranitidine (50 mg/kg). This study indicates that both flaxseed
oil and flaxseed mucilage can provide a cytoprotective effect against ethanol-induced
gastric ulcers in rats.
December 2008Libyan Journal of Medicine 3(4):166-9 , AOP: 080612
researchgate.net
Effect of Topical Linum usitatissimum on Full Thickness Excisional Skin
Shima Rafiee, Noushin Nekouyian, Sahar Hosseini, Farhad Sarabandi, Mehdi Chavoshi-Nejad,
Maryam Mohsenikia, Soheila Yadollah-Damavandi, Amin Seifaee, Ehsan Jangholi,
Dorna Eghtedari, Hanieh Najafi, and Soheil Ashkani-Esfahani*
Abstract
Background: Wound healing includes processes such as cell migration, extracellular
matrix deposition, remodeling, and angiogenesis. In addition, antioxidative
and anti-inflammatory reactions play key roles in the process of wound healing.
Previous studies
showed that Linum usitatissimum (LU) had anti-inflammatory, antimicrobial, and
antioxidant activities. LU also stimulates fibroblast proliferation in the skin
tissue.
Objectives: Herein, we studied the effects of topical LU on the wound healing
process in rat models, according to histomorphometrical and stereological parameters.
Methods: In this experimental study, 48 male rats (Wistar; 200 ± 20 grams)
were randomly separated into four groups (n = 12):
5% LU gel-treated (E1), 10% LU gel-treated (E2), gel base-treated (C2), and
the control group (C1), which received no treatment. A full thickness circular
wound was created on the neck in each rat. At the end, the stereological evaluations,
including wound closure rate, collagen, vascular and hair follicle density estimation,
fibroblast proliferation, vascular length density, and mean diameter were performed.
The data was analyzed, and P < 0.05 was considered statistically significant.
Results: The average of the wound areas, collagen bundle synthesis, vascularization,
and hair follicles in the LU-treated groups were significantly higher than the
control group (P < 0.05). According to the estimated parameters, the contrast
between E1 and E2 was insignificant.
Conclusions: Overall, topical LU showed the potential to enhance the wound healing
process and tissue regeneration. However,
more studies, particularly clinical trials, are highly recommended on LU and
its mixture with other healing agents to find more
potent treatments.
Trauma Mon. 2017 November; 22(6):e39045. Published online 2016 September 13.
doi: 10.5812/traumamon.39045. Accepted 2016 September 06.
cdn.neoscriber.org