PREPARATIONS:
Decoction. Rhizome 12-30 g each dose.[1,3]
Flowers 3-9 g each dose.[1] Rhizome
1-30 g.[2]
HABITAT: Found growing in wild places,
roadsides and field edges. DESCRIPTION: Perennial herb. Rhizomes; horizontal, covered externally
by scales. Leaves; clustered, linear or linear-lanceolate, margins coarse. Blooms;
in summer, flower style appearing from leaf cluster to form inflorescence, densely
covered by silky white hairs. References
[1] Barefoot Doctor's Manual- 1977 Prepared by the Revolutionary Health Committee
of Hunan Province. Original Chinese manual- Victor W. Sidel. Originally published
by Dr Joseph Quin and the Fogarty International centre, Bethdesda (1974).
Madrona Publishers Seattle Washington ISBN 0-914842-52-8
[2] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture
and Herbalism 1981- Henry Lu Chinese Foundations of Natural Health- The Academy
of Oriental Heritage, Vancouver, Canada.
[3] Translation notes from Gary Seiford and Hocu Huhn- NSW College of Natural
Therapies. Sydney Australia (1982). Images
1. en.wikipedia.org
by Mark Marathon CC BY-SA 3.0
2. [1]
3. beforeitsnews.com
Inner Path can not take any responsibility for any adverse effects from
the use of plants. Always seek advice from a professional before using a plant
medicinally. References
Anti-Cancer Effects of Imperata cylindrica Leaf Extract on Human Oral
Squamous Carcinoma Cell Line SCC-9 in Vitro.
Keshava R, Muniyappa N, Gope R, Ramaswamaiah AS. Abstract
Imperata cylindrica, a tall tufted grass which has multiple pharmacological
applications is one of the key ingredients in various traditional medicinal
formula used in India. Previous reports have shown that I. cylindrica plant
extract inhibited cell proliferation and induced apoptosis in various cancer
cell lines. To our knowledge, no studies have been published on the effect of
I. cylindrica leaf extract on human oral cancers. The present study was undertaken
in order to evaluate the anticancer properties of the leaf extract of I. cylindrica
using an oral squamous cell carcinoma cell line SCC-9 as an in vitro model system.
A methanol extract from dried leaves of I. cylindrica (ICL) was prepared by
standard procedures. Effects of the ICL extract on the morphology of SCC-9 cells
was visualized by microscopy. Cytotoxicity was determined by MTT assay. Effects
of the ICL extract on colony forming ability of SCC-9 cells was evaluated using
clonogenic assay. Cell cycle analysis was performed by flow cytometry and induction
of apoptosis was determined by DNA fragmentation assay. The ICL extract treatment
caused cytotoxicity and induced cell death in vitro in SCC-9 cells in a dose-dependent
manner. This treatment also significantly reduced the clonogenic potential and
inhibited cell proliferation by arresting the cell cycle in the G2/M phase.
Furthermore, DNA fragmentation assays showed that the observed cell death was
caused by apoptosis. This is the first report showing the anticancer activity
of the methanol extracts from the leaves of I. cylindrica in human oral cancer
cell line. Our data indicates that ICL extract could be considered as one of
the lead compounds for the formulation of anticancer therapeutic agents to treat/manage
human oral cancers. The natural abundance of I. cylindrica and its wide geographic
distribution could render it one of the primary resource materials for preparation
of anticancer therapeutic agents.
PMID: 27221872 Asian Pac J Cancer Prev. 2016;17(4):1891-8. ncbi.nlm.nih.gov