Ocimum basilicum.   Sweet basil  Family: Labiatae        
Cultivated worldwide. This plant should not be conufed with Wild Basil, which is Calamintha clinapodium- and has clusters of small red flowers.

PART USED: Whole herb  
ACTIONS
1. GROUP: Herbs for the mind and emotions - Cephalics.[1]
2. Antispasmodic.[1] Analgesic.[3]
3. Antiseptic.[1] Antibacterial.[3]
4. Stomachic..[1] Carminative.[3]
5. Thymoleptic.[1]
6. Aromatic.[3]
7. Vermifuge- see research[3]
INDICATIONS
1. Mental fatigue or weakness, indecision depression. Insomnia especially of children anxiety.[1]
2. Nausea and vomiting.[1] Dyspepsia. Colic.[1]
3. Migraine.[1]
4. Thrush. Tonsillitis. Coughs including whooping cough. Inflammatory ear conditions.[1]
5. Vertigo.[1]
6. Diseases of the kidney.[3]
PREPARATIONS
Infusion  (S)  60-100 ml
Decoction-   A small handful fresh herb to 1000 ml in cupful doses
Local: Footbaths and handbaths.  Use the fresh juice as ear-drops.[1]


PART USED: Essential Oil     
DESCRIPTION: Light green in color.
ACTIONS
1. Refreshes, brings clarity and helps stamina.[2]
INDICATIONS
1. Headache. Head colds- Used in a massage oil blend massaging the neck, temples and forehead.[2]
2. Strengthening- Use in a massage oil blend to relieve muscular cramping and stress and strain.[2]
3. Useful for tired students, writers, office workers or long distance drivers.[2]
CONTRAINDICATIONS: Pregnancy. May be irritating to sensitive skin.[2]
PREPARATIONS
Vaporization. Top note.[2]

DESCRIPTION: An annual herb reaching about 20 cm, with an erect stem and numerous branches. the leaves are opposite, stalked, broadly ovate and pointed; usually pale green and dotted with oil glands, however purple varieties occur as ornamentals. The flowers, which appear in summers, are small and whitish, sometimes with a purple tinge in long loose spikes.
References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.

Constituents.

Research.
Some of the vermicidal properties have been confirmed, and the antibacterial effects in acne sufferers demonstrated, in clinical trials in India.[1,2]
The oil is reportedly non-toxic,[3] however estagole is a known hepatocarcinogen in animals.[4]
References
1. Jain, M. L. and Jain, S. R. (1972) Planta Med. 22, 66
2. Balambal, R. et al, (1985) J. Assoc. Phys. (India) 33 (8) 507
3. Opdyke, D. L. J. (1973) Food Cosmetics. Toxicol. 11, 867
4. Miller, El. C. et al. (1983) Cancer research 43, 1124

Antiviral activities of extracts and selected pure constituents of Ocimum basilicum. Chiang LC1, Ng LT, Cheng PW, Chiang W, Lin CC.
Abstract: Ocimum basilicum (OB), also known as sweet basil, is a well known medicinal herb in traditional Chinese medicine preparations. In the present study, extracts and purified components of OB were used to identify possible antiviral activities against DNA viruses (herpes viruses (HSV), adenoviruses (ADV) and hepatitis B virus) and RNA viruses (coxsackievirus B1 (CVB1) and enterovirus 71 (EV71)). 2. The results show that crude aqueous and ethanolic extracts of OB and selected purified components, namely apigenin, linalool and ursolic acid, exhibit a broad spectrum of antiviral activity. Of these compounds, ursolic acid showed the strongest activity against HSV-1 (EC50 = 6.6 mg/L; selectivity index (SI) = 15.2), ADV-8 (EC50 = 4.2 mg/L; SI = 23.8), CVB1 (EC50 = 0.4 mg/L; SI = 251.3) and EV71 (EC50 = 0.5 mg/L; SI = 201), whereas apigenin showed the highest activity against HSV-2 (EC50 = 9.7 mg/L; SI = 6.2), ADV-3 (EC50 = 11.1 mg/L; SI = 5.4), hepatitis B surface antigen (EC50 = 7.1 mg/L; SI = 2.3) and hepatitis B e antigen (EC50 = 12.8 mg/L; SI = 1.3) and linalool showed strongest activity against AVD-II (EC50 = 16.9 mg/L; SI = 10.5). 3. No activity was noted for carvone, cineole, beta-caryophyllene, farnesol, fenchone, geraniol, beta-myrcene and alpha-thujone. 4. The action of ursolic acid against CVB1 and EV71 was found to occur during the infection process and the replication phase. 5. With SI values greater than 200, the potential use of ursolic acid for treating infection with CVB1 and EV71 merits further investigation.
Clin Exp Pharmacol Physiol. 2005 Oct;32(10):811-6. ncbi.nlm.nih.gov

The effects of green Ocimum basilicum hydroalcoholic extract on retention and retrieval of memory in mice Shadi Sarahroodi, Somayyeh Esmaeili, Peyman Mikaili, Zahra Hemmati, and Yousof Saberi
Abstract: The purpose of this study was evaluation of green Ocimum basilicum (sweet basil) hydroalcoholic extract on memory retention and retrieval of mice by using passive avoidance apparatus. For this purpose, after weighting, coding and classifying the mice, they were grouped (n = 8) as follow as: test groups (electric shock plus sweet basil extract by doses: 100, 200, 400 and 800 mg/kg, i.p.), control group (Only electric shock) and blank group (electric shock plus normal saline). In all mentioned groups delay time of leaving the platform for both retention and retrieval test of memory was measured. In retention test, sweet basil extract was administered immediately after receiving electric shock and in retrieval test it was administered 24 hours after receiving electric shock. The results indicated that hydroalcoholic extract of green Ocimum basilicum significantly (P < 0.05) increased memory retention. The best response was achieved with 400 mg/Kg of the extract. Also, results showed that sweet basil extract significantly (P < 0.05) increased memory retrieval and the best result was achieved with 400 mg/Kg too. It can be concluded that memory enhancing effects of green Ocimum basilicum is because of antioxidant activity of flavonoids, tannins and terpenoids. Anc Sci Life. 2012 Apr-Jun; 31(4): 185–189. doi: 10.4103/0257-7941.107354 ncbi.nlm.nih.gov

Hypolipidaemic activity of aqueous Ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property. Amrani S, Harnafi H, Bouanani Nel H, Aziz M, Caid HS, Manfredini S, Besco E, Napolitano M, Bravo E.
Abstract: Hyperlipidaemia, atherosclerosis and related diseases are becoming a major health problem in developing countries. Ocimum basilicum is one of the medicinal plants widely used in Morocco to reduce plasma cholesterol and to reduce the risk of atherosclerosis-related diseases. However, mechanisms underlying the reported hypolipidaemic effect of this plant have not been investigated. This study evaluates the lipid lowering effect of aqueous Ocimum basilicum extract in Triton WR-1339-induced hyperlipidaemic rats. Hyperlipidaemia was developed in animals by intraperitoneal injection of Triton (200 mg/kg). After injection of Triton the animals were divided into three treatment groups: hyperlipidaemic, hyperlipidaemic plus herb extract and hyperlipidaemic plus fenofibrate treated rats. At 7 h after the Triton injection, levels of plasma cholesterol, triglycerides and LDL-cholesterol in rats treated also with the Ocimum basilicum extract (0.5 g/100 g body weight) were, respectively, 50%, 83% and 79% lower than Triton-treated rats and HDL-cholesterol was 129% higher than in rats given Triton alone. At 24 h following Ocimum basilicum administration, total cholesterol, triglycerides and LDL-cholesterol levels decreased by 56%, 63% and 68%, respectively, in comparison with the Triton treated group and HDL-cholesterol was not increased significantly. The hypolipidaemic effect exerted by Ocimum basilicum extract was markedly stronger than the effect induced by fenofibrate treatments. Further it was demonstrated that Ocimum basilicum aqueous extract displayed a very high antioxidant power. These results indicate that Ocimum basilicum extract may contain hypolipidaemic and antioxidant substances and its use as a therapeutic tool in hyperlipidaemic subjects may be of benefit and encourage further investigation in this field. Phytother Res. 2006 Dec;20(12):1040-5. ncbi.nlm.nih.gov