Helichrysum stoechas. Gnaphalium stoechas, G. citrunum, Stoechas citrina   Eternal flower, Goldilocks Family: Asteraceae 
PART USED: Tops
TASTE: Bitter, pungent   ODOR: Faint
ACTIONS
1. Expectorant.[1]
HABITAT: A garden plant in Britain and Europe.
DESCRIPTION: Yellow flowers arranged in a crowded corymb, the outer florets ar yellow and shiny.
References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.
Constituents
References

Chemical and antibacterial studies of two Helichrysum species of Greek origin.
Chinou IB, Roussis V, Perdetzoglou D, Tzakou O, Loukis A.
Abstract
The chemical composition of the essential oils obtained from the aerial parts of Helichrysum stoechas ssp. barrelieri and H. taenari was analysed by GC and GC/MS. From the thirty-nine identified constituents representing the 73.87% and 87.41% of the two oils, respectively, beta-elemene, beta-caryophyllene, geraniol, and camphene were the major components. Furthermore, it was found that the oils exhibited significant antibacterial activity against six Gram (+/-) bacteria.
PMID: 9140235 DOI: 10.1055/s-2006-957641 Planta Med. 1997 Apr;63(2):181-3. ncbi.nlm.nih.gov

Cytogenetic effects of nine Helichrysum taxa in human lymphocytes culture
Halil Erhan Eroglu,corresponding author Ahmet Aksoy, Ergin Hamzaoglu,Ümit Budak, and Sevil Albayrak
Abstract
Helichrysum Mill. (Asteraceae) species have been used in folk medicine for thousands of years in the world. The in vitro cytogenetic effects in human lymphocytes of nine Helichrysum taxa used in Turkey folk medicine were investigated. Blood samples were obtained from healthy donors, non-smoking volunteers, which were incubated and exposed to increasing concentrations of methanol extracts of Helichrysum taxa (0.01, 0.05, 0.1, 0.5 and 1 mg/mL). The inhibitory effects of H. stoechas (L.) Moench subsp. barrelieri (Ten.) Nyman, H. armenium DC. subsp. armenium, H. armenium DC. subsp. araxinum (Kirp.) Takht., H. plicatum DC. subsp. plicatum, H. compactum Boiss. and H. artvinense P.H.Davis & Kupicha on the mitotic index and replication index indicate that these taxa can have genotoxic and mutagenic effects. They should therefore not be used freely in alternative medicine although their antiproliferative activity may suggest anticarcinogenic properties. Increase effects of H. stoechas subsp. barrelieri, H. armenium subsp. armenium, H. armenium subsp. araxinum, H. chasmolycicum P.H.Davis, H. plicatum subsp. plicatum, H. compactum and H. artvinense on the micronucleus rates showed that these taxa can have genotoxic and carcinogenic effects.
Cytotechnology. 2009 Jan; 59(1): 65–72.
Published online 2009 Apr 24. doi: 10.1007/s10616-009-9193-0
PMCID: PMC2677150
PMID: 19396560 ncbi.nlm.nih.gov

LC coupled to ion-trap MS for the rapid screening and detection of polyphenol antioxidants from Helichrysum stoechas.
Carini M1, Aldini G, Furlanetto S, Stefani R, Facino RM.
Author information
Abstract
Liquid Chromatography-Ion Trap Mass Spectrometry with an atmospheric pressure chemical ionization (APCI) interface in the negative and positive-ion modes in parallel to UV-diode-array detection (DAD), was applied for the rapid detection/characterization in crude extracts of the water-soluble antioxidant phenolics from Helichrysum stoechas. APCI-MS provides unequivocal molecular weight data of these compounds and useful information about their structures (diagnostic fragments ions), which were confirmed by the UV-DAD fingerprints. This combined approach allows the identification of ten constituents, including the three naturally occurring isomers of caffeoylquinic acid (CGAs), namely neo-chlorogenic acid, chlorogenic acid and crypto-chlorogenic acid, 2 isomeric dicaffeoyl quinic acids, 2 isomeric naringenin glucosides, quercetin, kaempferol and apigenin glucosides and a tetrahydroxychalcone-glucoside. The water-soluble extract from H. stoechas, standardized in both total polyphenol and kaempferol-3-glucoside content, exhibits strong antioxidant activity in vitro when tested in both artificial membrane systems (phosphatidylcholine liposomes) and in a cell model (rat erythrocytes).PMID: 11199231 J Pharm Biomed Anal. 2001 Jan;24(3):517-26. ncbi.nlm.nih.gov

Isolation and identification of the antibacterial compounds from Helichrysum stoechas.
Ríos JL1, Recio MC, Villar A.
Author information
Abstract
Fractionation of the dicholoromethane extract of the aerial parts of Helichrysum stoechas yielded seven isolates (1-7), which exhibited varying antimicrobial activity against Gram-positive bacteria. Pure compounds 1-3 have been previously reported in the same species and 4 and 5 were identified as italipyrone and plicatipyrone, previously isolated from H. italicum and H. plicatum. The two other isolates are helipyrone (6) and homoarenol (7) mixed with related substances. Compound 6c (4,4'-dihydroxy-5,6,5',6'-tetramethyl-3,3'-methylen-di-pyr-2-one) and 6b helipyrone with one methyl substitution, have not been previously reported in other species.
PMID: 1943173 J Ethnopharmacol. 1991 May-Jun;33(1-2):51-5. ncbi.nlm.nih.gov