HABITAT: Grows along stream edges, roadsides and hillsides. DESCRIPTION: Annual herb. Stem; fine and slender, creeping, muliple-branched.
Leaves; opposite, interspaced or alternate, long oval, apex rounded-obtuse,
margins doubly serrated. Stem leaves; ooze white milky fluid when broken. Flowers;
in late summer, small axilary flowers, yellowish brown. Capsule; small, globular.
References
[1] Barefoot Doctor's Manual - 1977 Prepared by the Revolutionary Health Committee
of Hunan Province. Original Chinese manual- Victor W. Sidel. Originally published
by Dr Joseph Quin and the Fogarty International centre, Bethdesda (1974). Madrona
Publishers Seattle Washington ISBN 0-914842-52-8
[2] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture
and Herbalism 1981 - Henry Lu Chinese Foundations of Natural Health- The Academy
of Oriental Heritage, Vancouver, Canada. Images
1. greif.uni-greifswald.de
2. [1] Inner Path can not take any responsibility for any adverse effects
from the use of plants. Always seek advice from a professional before using
a plant medicinally
References
Anti-inflammatory components of Euphorbia humifusa Willd.
Luyen BT, Tai BH, Thao NP, Eun KJ, Cha JY, Xin MJ, Lee YM, Kim YH. Abstract
Two new compounds, euphorbinoside (1) and dehydropicrorhiza acid methyl diester
(2), along with 24 known compounds (3-26) were isolated from Euphorbia humifusa
Willd. The effects of these compounds on soluble epoxide hydrolase (sEH) inhibitory
activity were evaluated. Flavonoid compounds (10-21) exhibited high sEH inhibitory
activity. Among them, compounds 12, 13, and 19 greatly inhibited sEH enzymatic
activity, with IC50 values as low as 18.05±1.17, 18.64±1.83, and 17.23±0.84 μM,
respectively. In addition, the effects of these compounds on lipopolysaccharide
(LPS)-induced nitric oxide (NO) and tumor necrosis factor alpha (TNF-α) production
by RAW 264.7 cells were investigated. Compounds 3-6, 8, 18, 20-23, and 25-26 inhibited
the production of both NO and TNF-α, with IC50 values ranging from 11.1±0.9 to
45.3±1.6 μM and 14.4±0.5 to 44.5±1.2 μM, respectively.
Bioorg Med Chem Lett. 2014 Apr 15;24(8):1895-900. doi: 10.1016/j.bmcl.2014.03.014.
Epub 2014 Mar 15. ncbi.nlm.nih.gov