Pinellia
ternata.半夏 Bàn xià Pinellia
Family: Araliaceae
The name Ban xia- meaning half way through Summer, is the time around the summer
solstice when the Ban xia tuber can first be harvested and when nature’s Qi is
beginning to move downwards and inwards. PART USED:Tuber;
collected in Summer and Autumn, washed clean and dried in sunlight, and is called
dried Pinellia. But it is usually used after being further processed with Ginger
and Alum, and is hence called
prepared Pinellia.[3] FLAVOR:Pungent. TOXICITY:
Toxic- It is prepared to remove toxicity. CHANNELS: Spleen,
Stomach, Lung FUNCTION GROUP:
Antitussive and Expectorant Clearing- Cold Phlegm
1. Dry up Dampness.[1,2,3,4]Resolve phlegm.[1] Strengthens
Spleen.[1]
2. Causes rebellious Qi to descend to stop vomiting.[1,2,3,4]
3. Harmonizes the the Stomach and stops comiting.[4]
4. Dissipates nodules and reuduces distention.[4]
Disintegrating and resolving masses.
5. Stops bleeding and reduces inflammation.[1] INDICATIONS
1. Profuse sputum, cough with adverse upward flow of Qi,[4]
and vertigo, due to Dampness of the Spleen,[4]
to dispel Dampness and accumulation and retention of phlegm. Phlegm Cold in the
Lungs.[4] Bronchitis.[1]
Cough and asthma.
2. Nausea and vomiting due to adverse rising of the stomach Qi.[1,2,3,4]Vomiting
due to Cold Phlegm. Vomiting due to Stomach Heat. Vomiting during pregnancy. Vomiting
due to Stomach deficiency.[1] Local
distention in the chest and epigastrium.[4]
3. Feeling of stuffiness and distention in the chest and upper abdomen,
due to accumulation of Heat Phlegm. Globus hystericus. Goiter.
4. Subcutaneous nodules, pressure, distention, or pain due to Phlegm lingering
in the chest, phlegm nodules in the neck- such as those of goiter and scrofula,
or obstruction caused by Phlegm anywhere in the body.[4]
5. External application- Carbuncles, deep rooted carbuncles, lumbodorsal cellulitis,
and breast furuncles. Other suppurative infections on the skin.
6. Traumatic bleeding, poisonous snakebites, swollen abscesses.[1]
7. Rheumatism and arthralgia.[1] CONTRAINDICATIONS: It is antagonistic to Aconitum
carmichaeli- Aconite.[3,4] All cases
of bleeding, cough due to Yin deficiency, or depleted fluids.[4]
Use with caution in all cases with Heat.[4] COMPARISONS
Compared to Bei mu, Pinellia is more effective
in treating Phelgm Dampness, while the former herb is more effective in clearing
Phelgm Heat. Pinellia is also more effective in transforming Phelgm lodged in
the Stomach, while Fritiallaria is better for transforming Phlegm in in Lungs.
In general, however, the two are often used in concert to mutually enhance the
others therapeutic properties.
- Relaxing the Spirit: Nourishes
Heat Blood and Yin, calms the Shen. Tonifies and regulated the middle Heater.
harmonises Liver and Spleen Ziziphus
& Polygala- An shen ding zhi wan. - Upward disturbance of Wind Phlegm: Eliminates Phlegm,
subdues Internal Wind, strengthens the Spleen and dries Damp Pinellia,
Atractylodes, & Gastrodia- Ban xia bai zhu tian ma tang. - Emotional disorders with retention of Phlegm: Disperses
stagnant Qi, moves the Qi and dissipates lumps, direction rebellious Qi downwards,
transforms Phlegm Pinellia
and Magnolia- Ban xia hou po tang.
- Food stagnation obstructing the middle Heater (Stomach and Spleen):
Harmonizes and regulates the Spleen and Stomach, reduces food stagnationCitrus
& Crataegus- Bao he wan.
- Asthma due to Phlegm Heat: Diffuses
and redirects the Lung Qi downward, alleviates wheezing, transforms Phlegm, clears
Heat
Gingko Nut & Apricot seed- Ding chuan wan.
- Retention of Damp Phlegm due to Spleen Qi deficiency:
Dries Dampness, transforms Phlegm,
regulates the Qi and harmonizes the middle Burner
Citrus & Pinellia- Er chen wan. - Stagnation of Phlegm Heat in the Lungs and throat:Eliminates
Phlegm, Regulates Qi, disperses stagnation, drains Dampness, Clears Heat, and
relieves cough Platycodon
Combination- Jie geng wan. - Phlegm- Fluid retention in the Lung:Warms the Lung,
eliminates Phlegm-Fluid retention, relieves coughingHoelen
& Schizandra- ling gan jiang wei xing xia ren tang. - Spleen and Stomach Qi deficiency with Phelgm
Damp retention: Tonifies the Qi, strengthens
the spleen and Stomach, dries Dampness, transforms Phlegm, regulates the Qi
and harmonizes the middle Heater Six
major herbs combination- Liu jun zi wan. - Deficiency of Stomach Qi and Yin with
rebellious Qi, or deficiency Heat in the Stomach with damage to Lung Yin and
fluids, or deficiency of Stomach Yin with deficiency Fire and ascent of rebellious
Qi: Tonifies and nourishes Stomach Qi and Yin, Nourishes Lung Yin,
promites production of body fluids, descends rebellious Qi Ophiopogon
Combination- Mai men dong tang - Qi stagnation and retention of Dampness in the
Stomach and Intestines:Regulate the Liver and Stomach, disperses
Qi stagnation and Damp retention Saussurea
Combination- Mu xiang shun qi wan.
- For stagnation of heat and Phlegm in the Lung:Clears
Heat, eliminates Phlegm, Descends rebellious Qi, alleviates coughing Zhi
shi and Arisaema- Qing qi hua tang wan. - Exterior Wind Cold in patients with Lung and Spleen Qi deficiency
with Phlegm Damp retention:Releases
exterior Wind Cold, disperses stagnant Qi and harmonises the middle Heater,
transforms Phlegm, tonifies QiGinseng & Perilla Combination- Shen
su yin- - Phlegm-Cold obstructing the Lung with Kidney unable to grasp
the Qi (Kidney Yang deficiency):Redirects
the Qi downwards, stops coughing and wheezing, warms the Lung and transforms PhlegmPerilla
fruit combination- Su zi jiang qi wan. - Phlegm and Heat or disharmony between Gall Bladder and Stomach:
Dries Dampness and transforms Phlegm, regulates
the Qi and harmonizes the Stomach, clears Heat from the Gallbladder and eliminates
irritabilityBamboo
& Hoelen- Wen dan tang. - Uterus deficient- Cold with Blood stagnation:Warms
the uterus and dispels Cold, nourishes the Blood and dispels blood stasis Danggui
& Evodia- Wen jing tang. - Spleen Qi deficiency and retention of Phlegm Damp: Tonifes
Qi of Spleen and Stomach, regulates Qi and harmonises middle Heater, dispels
Cold, Dampness and PhlegmSaussurea
& Cardamon- Xiang sha liu jun zi wan. - Deficiency of the Stomach and Spleen with stagnation of Dampness:
Tonifies the Qi, strengthens the Spleen and Stomach, transforms Phlegm and Dampness,
regulates the Qi and harmonizes the middle Heater, alleviates painCyperus
& Cardamon- Xiang sha yang wei wan. - External Pathogen
lodges at the Shao yang level (half exterior, half interior): Harmonizes
the releases Shao Yang stage disorders, tonifies the QiMinor
Bupleurum Combination- Xiao chai hu wan. - Exterior Wind Cold with retention of Phlegm and Fluids: Releases
exterior Wind Cold, warms the Lung and Spleen to transform Phlegm and congested
fluids, directs rebellious Qi downwards to relieve cough and dyspnea Minor
Blue dragon combination- Xiao qing long wan. - Damp Heat painful obstruction: Clears Heat,
eliminates Dampness, unblocks the Channels and Collaterals, relieves painful
obstructionStephania
& Blue atractylodes- Xuan bi tang. - Heat Qi and Blood deficiency: Tonifies Heart Qi, Nourishes
Heart Blood, calms the Shen and tranquilizes the mindAstragalus
& Zizyphus- Zao ren yang xin wan.
- Epigastric and abdominal distention, nausea, and vomiting due to disharmony
of the Stomach Qi. This cmbination is also used for productive cough and a stifliing
sensation in the chest due to obstruction of Phelgm Dampness or Spleen Qi deficiency.
use with Citrus tangerina- Chen pi.
- Epigastric distention and indigestion due to a simultaneous invasion of hot
and cold pathogenic influences into the Stomach, with Coptis
chinensis- Huang lian.
- Phlegm Heat induced rebellious Qi with cough, nausea, and vomiting. Use with
Scutellaria baicalensis- Huang qin.
- Feeling of distention in the chest, cough, and vomiting due to Phlegm Heat obstructing
the interior. Use with Trichosanthes kirilowii-
Gua lou.
- Phlegm induced cough, vomiting, and epigastric and abdominal distention. Use
wtih Magnolia officinalis- Hou po.
- Phlegm Heat induced insomnia with Prunella
vulgaris- Xia ku cao.
- Scrofula or Phlegm Dampness induced cough. Use with Fritillaria
thunbergii- Zhe bei mu.
PREPARATIONS: Decoction.
Tuberous stems 4-9 g.[1,2,3]
4-12 g.[4] For external use, the fresh
herb crushed and applied as a poultice for skin eruptions.[1,2]
Raw pinellia ternata tuber is toxic and is only used externally to reduce ulcerations,
deep rooted sores, and carbuncles.[4]
Preparation of Ban xia is achieved by deep frying with ginger, vinegar, or albumen.
HABITAT: Grows wild in shady and damp grass thickets on mountain sides
and stream edges. DESCRIPTION: Pinellia is a perennial herb. Subterranean rhizome; globular
or flat-globular. Leaves; appearing terminally from stem, long petioles, annual
leaves single, ovate cordate, becoming 2 to 3 years later 3 leaflet compound leaves,
leaflets elliptical-lanceolate, apexes pointed, bases narrow, 3 leaflets combining
to form bulbels. Flowers; in summer, yellowish green, in terminal spike inflorescence,
spathe below inflorescence. Berry; small ovate and green. References
[1] Barefoot Doctor's Manual- 1977 Prepared
by the Revolutionary Health Committee of Hunan Province. Original Chinese manual-
Victor W. Sidel. Originally published by Dr Joseph Quin and the Fogarty International
centre, Bethdesda (1974). Madrona Publishers Seattle Washington ISBN 0-914842-52-8
[2] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture
and Herbalism 1981- Henry Lu Chinese Foundations of Natural Health- The Academy
of Oriental Heritage, Vancouver, Canada.
[3] The Chinese Materia Medica A practical English- Chinese Library of Traditional
Chinese Medicine Publishing House of Shanghai University of Traditional Chinese
Medicine. Director Hu Ximing ISBN 7-81010-111-X/R-110
[4] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7 Images
1. dentomed.u-toyama.ac.jp
2. dentomed.u-toyama.ac.jp
3. [1]
Inner Path can not take any responsibility for any adverse effects from the
use of plants. Always seek advice from a professional before using a plant medicinally.Constituents
Coniine, protoanemonin, homogentisic acid,
nicotine, aspartic acid, glutamic acid, arginine, b-sitosterol, cholesterol. References
[1] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble-
Eastland Press 1986 Seattle Washington ISBN 0-939616-15-7
The LD50 of unprepared rhizome
Pinellia injected intraperitoneally into mice is apporoximately 13g/kg. In studies
on mice the unprepared herb was the most toxic form, that prepared with ginger
second, and that with albumen being the least toxic. One report detailed the
effect of overdosage of this herb in four people who ate it as food and in very
large amounts. The most promient symptoms were a feeling of burning and numbness
in the throat and lips, queasy stomach and neasea, and a feeing of pressure
in the chest. On person recovered without any help, and the others were cured
with oral administration of raw ginger. References
[1] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7
Compared with Fritillaria
cirrhosa- Chuan bei mu, Ban xia is more effecting in treating Phlegm Dampness,
while the former herb is more effective in clearing Phlegm Heat. Ban xia is
also more effective in transforming Phelgm lodged in the Stomach, while Chuan
bei mu is better for transforming Phlegm in the Lungs. In general, however,
the two are often used together to mutally enhance the others therapeutic properties. References
[1] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7
Research
Anti-obesity effect of Pinellia ternata extract in Zucker rats.
Kim YJ, Shin YO, Ha YW, Lee S, Oh JK, Kim YS. Abstract
Pinellia ternata is known as the herb effective in removing dampness-phlegm, one
of the causes of obesity in traditional Korean medicine. Pinellia ternata water
extract (PE) was fed to rats after mixing with diet once a day (400 mg x kg(-1))
for 6 weeks. We investigated its effect on the thermogenesis and fatty acids oxidation
with obese Zucker rats. We also determined the gene expression of uncoupling protein
1 (UCP1), peroxisome proliferators-activated receptor alpha (PPARalpha), and PPARgamma
coactivator 1alpha (PGC1alpha). The PE treatment lowered the levels of triglyceride
and free fatty acids (p<0.05) in blood of the obese rats and the body weight
was also reduced slightly. It was also observed that PE significantly increased
the expression of both UCP1 mRNA in brown adipose tissue (BAT) (p<0.001) and
PPARalpha and PGC1alpha mRNA in white visceral adipose tissue (WAT) (p<0.05
and p<0.001, respectively), which may cause a reduction of obesity. These results
suggested that PE would be able to affect anti-obesity through thermogenesis and
fatty acid oxidation.
PMID: 16755034 Biol Pharm Bull. 2006 Jun;29(6):1278-81. ncbi.nlm.nih.gov
Effect of Pinellia ternata tuber on the efferent activity of the gastric
vagus nerve in the rat.
Niijima A, Okui Y, Kubo M, Higuchi M, Taguchi H, Mitsuhashi H, Maruno M. Abstract
Effect of intraduodenal infusion with the hot aqueous extract of Pinellia ternata
tuber on the efferent discharges in the gastric branch of the vagus nerve was
observed in the anesthetized rat. The infusion of the extract in doses of 2-15O
mg per animal (c.a. 300 g, b.wt.) resulted in a dose-related increase in efferent
activity of the vagal gastric nerve. The enhancement of the nerve activity following
administration of 150 mg of this substance lasted longer than 90 min. It was observed
that the suppressive effect on vagal gastric activity due to apomorphine and copper
sulfate was antagonized by prior administration of the extract. From these observations
it is suggested that Pinellia tuber acts as a facilitatory agent on gastric function.
PMID: 8348334 Brain Res Bull. 1993;32(2):103-6. ncbi.nlm.nih.gov
Pinellia ternata (Thunb.) Makino Preparation promotes sleep by increasing REM
sleep.
Lin S, Nie B, Yao G, Yang H, Ye R, Yuan Z. Abstract
Pinellia ternata (Thunb.) Makino Preparation (PTP) is widely used to treat insomnia
in traditional Chinese medicine; however, its specific role is not clear. In
this study, PTP was prepared at three concentrations. For locomotor activity
tests, mice were treated with PTP and evaluated for 14 days. For polygraph recordings,
mice were treated for 14 days and recorded after treatment. The main chemical
constituents in PTP were identified by Ultra performance liquid chromatography/quadrupole
time spectrometry (UPLC/Q-TOF-MS). The results showed that 0.9 g/mL PTP significantly
reduced locomotor activity. The effect was related to the time of treatment.
PTP reduced wakefulness and increased sleep in mice. Furthermore, PTP promoted
sleep by increasing the number of REM sleep episodes with a duration of 64-128s
and increasing the number of transitions from NREM sleep to REM sleep and from
REM sleep to wakefulness. A total of 17 compounds were identified.
PMID: 29764203 DOI: 10.1080/14786419.2018.1474466 Nat Prod Res. 2018 May 15:1-4.
doi: 10.1080/14786419.2018.1474466. [Epub ahead of print] ncbi.nlm.nih.gov
Effects of Pinellia ternata (Thunb.) Berit. on the metabolomic profiles
of placenta and amniotic fluid in pregnant rats.
Xie HH, Xu JY, Xie T, Meng X, Lin LL, He LL, Wu H, Shan JJ, Wang SC. Abstract
ETHNOPHARMACOLOGICAL RELEVANCE:
Banxia (BX) is the root of Pinellia ternata (Thunb.) Berit. Its processed products,
such as Jiang Banxia (JBX), have been clinically used in traditional Chinese
medicine to treat vomiting, coughing, and inflammation. However, data for their
safety for pregnant women are contradictory and confusing.
AIM OF THE STUDY:
To further explore the safety of BX, an ultra-performance liquid chromatography
coupled with liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass
spectrometry (GC-MS) metabolomics approach was used to evaluate the metabolic
perturbation in pregnant rats caused by BX and JBX.
MATERIALS AND METHODS:
Placenta and amniotic fluid samples were collected from control Sprague-Dawley
pregnant rats and exposed to BX suspension and JBX decoction (1.434g/kg/day).
Samples were analyzed using LC-MS and GC-MS. The acquired MS data of above samples
were further subjected to multivariate data analysis, and the significantly
altered metabolites were identified. The associated pathways were constructed
using MetaboAnalyst 3.0.
RESULTS:
The weight and histopathology of the placenta from each group of rats had no
definite difference. However, we found 20 differential endogenous metabolites
that changed significantly in the placenta and amniotic fluid samples. The alterations
of identified metabolites indicated a perturbation in glycerophospholipid metabolism,
amino acid metabolism, and carbohydrate metabolism in pregnant rats exposed
to BX and JBX.
CONCLUSION:
In summary, this work suggested that oral administration of BX and JBX may induce
disturbances in the intermediary metabolism in pregnant rats. This work contributes
to further understanding the safety of BX and its processed products.
PMID: 26923539 DOI: 10.1016/j.jep.2016.02.030 J Ethnopharmacol. 2016 May 13;183:38-45.
doi: 10.1016/j.jep.2016.02.030. Epub 2016 Feb 24. ncbi.nlm.nih.gov