Phellodendron
chinense. P. amurense, P. wilsoni黄柏Huáng
bǎi,
Huang bo
Phellodendron, Cork
treeFamily:
Rutaceae PART USED: Bark- harvested
in Spring of about 10 year old plants. FLAVOR:Bitter
CHANNEL: Kidney, Bladder, Large Intestine- lower organs in body. FUNCTIONS GROUP: Clearing
Internal Heat- Drying Dampness
1. Drains Damp Heat-[1] particularly
from the lower Burner.[5] 2. Purges excess Fire and counteract toxic effects.[1,5]
3. Drains Kidney Fire.[5] Clearing
empty Heat.
4. Resolve Blood congestion.[4] ACTIONS
Antibacterial-[4]
especially useful in dysentery, diphtheria, lung infections and meningitis,
antiviral- its effects are quite similar to Huang lian but milder, astringent,[4]
antitoxic, decongestive, diuretic,[4]
strengthens stomach secretion.[4]
Antifungus.[4]
INDICATIONS
1. Damp Heat syndromes
- Atrophe of muscles of legs due to Damp Heat: Paralysis and numbers of lower
limbs.[4] Sciatica.[4]
Lameness, paralysis.[1] Damp Heat
pouring downward or Hot leg Qi with such symptoms as red, swollen, and painful
knees, legs, or feet.[5]
-Dysentery[1,5] due to Damp Heat[4]
with symptoms of fever,[1] abdominal
pain, diarrhea.[1] Purulent and bloody
stool, and tenesmus.[1,5] Jaundice.[1]
Gonorrhea.[1] Hemorrhoids.[1]
Enteritis. Constipation.[4]
-Jaundice due to Damp Heat.[5]
-Leukorrhea-[1]Bloody vaginal discharge.[1]
Yellow vaginal discharge.[5]
- Urinary tract infections with dysuria. Gonorrhea. Prostatitis.
2. Drains Fire and relieves toxicity for various infections on the skin such
as boils.[1] Sores, swelling,
ulcers. Fire toxin generated sores and damp lesions of the skin.[5]
Eczema. Canker sores.[1] Hemorrhoids.
Burns and scalds. Impetigo.The drug can be used internally or externally in
conjunction with other drugs according to the actual conditions.
3. Exuberance of Fire due to Yin deficiency marked by tidal fever, hectic
fever with night seat, and emission. Aching bones, conjunctivitis, tinnitus.[1,4]
Dry throat.[4] Ascending Kidney Fire
with signs of Yin deficiency such as bone steaming disorder, night sweats, afternoon
fevers and sweating.[5]
4. Hemorrhoids. PATENT COMBINATIONS
- Heat and Damp in lower Burner: Oliguria and dysuria.
Clears Damp-Heat, purges Fire, unblocks painful urinary dysfunction and promotes
diuresis Dianthus
Formula- Ba zheng san. - Diarrhea and dysentery due to Heat- Toxins invading Blood:
Clears Heat, revolves Toxicity, cools the Blood, relieves diarrhea and dysentery
Pulsatilla
Combination- Bai tou weng tang. - Upward disturbance of Wind Phlegm: Eliminates Phlegm,
subdues Internal Wind, stgrengthens the Spleen and dries Damp Pinellia
and Gastrodia- Ban xia bai zhu tiang ma tang - Damp Heat skin lesions. Damp Heat attacking the lower Burner: Clears
Damp-Heat, promotes Blood Circulation, eliminates ToxicityTokoro
and Coix- Bi xie sheng shi wan. - Deficiency of Yin and Blood and hyperactivity
of Fire:Enriches the Yin,
clears Heat, secures the exterior to stop sweatingDanggui,
Astragalus & Coptis- Dang gui liu huang wan. - Heat excess in the triple Burner or
excess. Heat Toxicity patterns: Drains
Fire and resolves ToxicityCoptis
& Scute- Huang lian jie du tang. - Damp Heat Bi syndrome: Clears Heat, eliminates
Dampness, unblocks the Channels and Collaterals, relieves Bi syndromeStephania
& Blue Atractylodes- Xuan bi tang. - Blood deficiency with Dampness
or mild Damp Heat obstructing the lower Burner:Tonfies Kidney
and nourishes Blood, clears Damp Heat and promotes circulation, arrests vaginal
dischargeLeukorrhea
Pills- Yu dai wan- Leukorrhea Pills. - Kidney Yin deficiency with hyperactivity of Yang (deficiency Heat):
Nourishes Liver and Kidney Yin, enriches Kidney Jing, Clears deficiency
Fire, Drains Damp-HeatAnemarrhena,
Phellodendron and Rehmannia- Zhi bai di huang wan.
CONTRAINDICATIONS: Phellodendron bark is bitter and
Cold and tends to cause impairment to the Stomach Qi. For this reason, it is
containdicated for Cold syndromes of deficiency type in the Spleen/Stomach.[4,5] COMPARISON:Huang Lian and Huang
qin are very similar and are often used in combination. Huang
qin sedates Lung Fire, Huang lian is
mainly used to sedate Stomach Fire and Huang bai is mainly used to disperse Damp
Heat- especially in the lower limbs.[4] PREPARATIONS:
Decoction Dried Bark 4-10 g.[1,2,3]
3-12 g.[5] Appropriate amount for
external usage.[1,3] Good quality
is thick, large, and bright yellow. References
[1] Barefoot Doctor's Manual- 1977 Prepared
by the Revolutionary Health Committee of Hunan Province. Original Chinese manual-
Victor W. Sidel. Originally published by Dr Joseph Quin and the Fogarty International
centre, Bethdesda (1974). Madrona Publishers Seattle Washington ISBN 0-914842-52-8
[2] A Complete English Dictionary of Medicinal Terms in Chinese Acupuncture
and Herbalism 1981- Henry Lu Chinese Foundations of Natural Health- The Academy
of Oriental Heritage, Vancouver, Canada.
[3] The Chinese Materia Medica A practical English- Chinese Library of Traditional
Chinese Medicine Publishing House of Shanghai University of Traditional Chinese
Medicine. Director Hu Ximing ISBN 7-81010-111-X/R-110.
[4] Translation notes from Gary Seiford and Hocu Huhn- NSW College of Natural
Therapies. Sydney Australia (1982).
[5] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7 Images
1. en.wikipedia.org
by Daderot Public Domain
2. fourflowerswellness.com
Inner Path can not take any responsibility for any adverse effects from the
use of plants. Always seek advice from a professional before using a plant medicinally. Constituents
Berberine, jatorrhizine, magnoflorine, phellodendrine, candicine, palmatine, menisperine,
obacunone, aboculactone, dictamnolide, abacunonic acid, lumicaeruleic acid, 7-dehydrostigmasterol,
b-sitosterol, campesterol. References
[1] Chinese Herbal Medicine Materia Medica- Dan Bensky and Andrew Gamble- Eastland
Press 1986 Seattle Washington ISBN 0-939616-15-7
Research
Phytochemical Quantification and the In Vitro Acetylcholinesterase Inhibitory
Activity of Phellodendron chinense and Its Components.
Kim YJ, Lim HS, Kim Y, Lee J, Kim BY, Jeong SJ. Abstract
The dried bark of Phellodendron chinense has been used as a traditional herbal
medicine to remove damp heat, relieve consumptive fever, and cure dysentery and
diarrhea. In the present study, we performed quantitative analyses of the two
components of P. chinense, phellodendrine and berberine, using high-performance
liquid chromatography. A 70% ethanol extract of P. chinense was prepared and the
two components were separated on a C-18 analytical column using a gradient solvent
system of acetonitrile and 0.1% (v/v) aqueous trifluoroacetic acid. The ultraviolet
wavelength used for detection was 200 nm for phellodendrine and 226 nm for berberine.
The analytical method established here showed high linearity (correlation coefficient,
≥0.9991). The amount of phellodendrine and berberine used was 22.255 ± 0.123 mg/g
and 269.651 ± 1.257 mg/g, respectively. Moreover, we performed an in vitro acetylcholinesterase
(AChE) activity assay and an amyloid-β aggregation test to examine the biological
properties of phellodendrine and berberine as therapeutic drugs for Alzheimer's
disease. Phellodendrine and berberine inhibited AChE activity in a dose-dependent
manner (IC50 = 36.51 and 0.44 μM, respectively). In contrast, neither phellodendrine
nor berberine had an effect on amyloid-β aggregation. The P. chinense extract
and phellodendrine, but not berberine, exhibited antioxidant activity by increasing
radical scavenging activity. Moreover, P. chinense demonstrated a neuroprotective
effect in hydrogen peroxide-treated HT22 hippocampal cells. Overall, our findings
suggest that P. chinense has potential as an anti-Alzheimer's agent via the suppression
of the enzymatic activity of acetylcholinesterase and the stimulation of antioxidant
activity.
Molecules. 2017 Jun 2;22(6). pii: E925. doi: 10.3390/molecules22060925.
PMID: 28574473 DOI: 10.3390/molecules22060925 ncbi.nlm.nih.gov