Chamaelirium luteum.   False unicorn, Helonias, Blazing star  Family: Liliaceae     
PART USED: Underground parts
TASTE: Astringent at first, bitter later ODORLESS
ACTIONS
GROUP: The Endocrine and Reproductive Systems- Reproductive System Tonics
1. Bitter tonic.[2]
2. Oestrogenic.[2]
3. Uterine tonic.[1,3]
4. Diuretic.[3]
5. Emetic.[3]
6. Anthelmintic. [3]
INDICATIONS
1. Suppressed menstruation especially with melancholy. Amenorrhea.[1] Menorrhagia with shortened menstrual cycle.[2] Ovarian dysmenorrhea.[1,2] Leukorrhea.[1,2] Vomiting during pregnancy.[1,2] As a miscarriage preventative or in the event of a threatened miscarriage.[1,2] As a uterine tonic after miscarriage.[2] Uterine weakness prolapse or malposition.[2] Menopausal problems.[2]
2. Anorexia.[2] Dyspepsia.[2]
3. Liver disorders.[2]
4. Disorders generally including albuminuria.[2]
SPECIFIC INDICATIONS: Amenorrhea.[1,3] and dysmenorrhea. Threatended miscarriage and also morning sickness.[3]
COMBINATIONS
- Combines well with Trillium.
PREPARATIONS: 3X/day
Dried roots  1-2 g,[1,2] or by infusion.
Fluid extract  1:1 in 45% alcohol 1-2 ml.[1,2] 2-4 ml.[3]
Tincture 1:5 in 45% alcohol  2-5 ml.[1,2]
SIDE EFFECTS: Large doses may cause nausea and vomiting.[1]


ORIGIN: North America
DESCRIPTION: The rhizome is about 2-3 cm long, 0.5-1 cm thick, nearly cylindrical, ringed transversely with a few stem scars on the upper surface and wiry rootlets on the lower. Fracture horny, greyish-white, showing numerous woody bundles in the centre.
References
Inner Path can not take any responsibility for any adverse effects from the use of plants. Always seek advice from a professional before using a plant medicinally.

Constituents

Research

Structure and bioactivity of steroidal saponins isolated from the roots of Chamaelirium luteum (false unicorn)
Victoria L Challinor 1, Julia M U Stuthe, Peter G Parsons, Lynette K Lambert, Reginald P Lehmann, William Kitching, James J De Voss
Affiliations expand
Abstract
Phytochemical investigation of Chamaelirium luteum ("false unicorn") resulted in the isolation of 15 steroidal glycosides. Twelve of these (1, 2, 4-9, 11-13, and 15) are apparently unique to this species, and eight of these (6-9, 11-13, and 15) are previously unreported compounds; one (15) possesses a new steroidal aglycone. In addition, the absolute configuration of (23R,24S)-chiograsterol A (10) was defined, and its full spectroscopic characterization is reported for the first time. The structures and configurations of the saponins were determined using a combination of multistage mass spectrometry (MS(n)), 1D and 2D NMR experiments, and chemical degradation. The antiproliferative activity of nine compounds obtained in the present work, and eight related compounds generated in previous work, was compared in six human tumor cell lines, with aglycones 3 and 10 and related derivatives 16, 17, 19, and 20 all displaying significant antiproliferative activity.
J Nat Prod 2012 Aug 24;75(8):1469-79. doi: 10.1021/np300393y. Epub 2012 Aug 10. PMID: 22880631 pubmed.ncbi.nlm.nih.gov